Fig. 5.

Cancer chemotherapy in vivo using PAA₆₈–b–PEG₈₆–b–PAA₆₈/MnO₂ (I), free DOX (II), and DOX-loaded PAA₆₈–b–PEG₈₆–b–PAA₆₈/MnO₂ (III) in MCF-7 tumor-bearing mice. a Digital images of tumors from MCF-7 tumor-bearing mice after 31 days in vivo cancer chemotherapy, scale bar: 1 cm. b Weight of tumor excised from MCF-7 tumor-bearing mice after treatment. c Body weight changes of MCF-7 tumor-bearing mice during therapy. d Tumor size change of MCF-7 tumor-bearing mice during therapy. e Histological analyses of major tissues from MCF-7 tumor-bearing mice after 31 days in vivo cancer chemotherapy, scale bar: 200 μm