Fig. 9.

a Mice were injected with either cskc-PPiP or cskc-PPiP@Ma NPs loaded with an IR probe for the indicated amount of time. b 3D reconstructed fluorescent image of signal in a mouse 48 h following cskc-PPiP@Ma treatment. c Heart (H), liver (Li), spleen (S), lung (Lu), kidney (K), and tumor (T) tissues isolated from the mouse in b. d PTX levels in the organs of mice following treatment using PTX, cskc-PPiP/PTX, PPC8/PTX@Ma, or cskc-PPiP/PTX@Ma (n = 4). e Body weight and f tumor volumes over 3 weeks in treated mice. g Tumor tissues from mice treated as indicated were assessed for apoptotic cells, shown in green. Scale bar = 100 μm.

Adapted from Ref. [126] with permission