Table 3.
Number of participants by cortisol test value category at baseline and end of study for participants in the Per Protocol population.
| Baseline |
End of Study |
|||||||
|---|---|---|---|---|---|---|---|---|
| Low | Normal | High | P | Low | Normal | High | P | |
|
AUCg(n) | ||||||||
| Placebo (n = 55) | 12 | 30 | 13 | 0.270 | 7 | 35 | 13 | 0.442 |
| Lpc-37 (n = 53) |
6 |
36 |
11 |
11 |
28 |
14 |
||
|
AUCi(n) | ||||||||
| Placebo (n = 55) | 22 | 28 | 5 | 0.413 | 15 | 36 | 4 | 1.000 |
| Lpc-37 (n = 53) |
16 |
34 |
3 |
15 |
34 |
4 |
||
|
Cortisol at awakening (n) | ||||||||
| Placebo (n = 55) | 16 | 26 | 13 | 0.425 | 12 | 34 | 9 | 0.265 |
| Lpc-37 (n = 53) |
14 |
31 |
8 |
19 |
26 |
8 |
||
|
Cortisol at 8pm (n) | ||||||||
| Placebo (n = 55) | 6 | 23 | 26 | 0.718 | 7 | 18 | 30 | 0.082 |
| Lpc-37 (n = 53) | 4 | 20 | 29 | 3 | 28 | 22 | ||
Abbreviations: AUCg, Area Under the Curve with respect to ground; AUCi, Area Under the Curve with respect to increase; High, above 75% quantile; Low, under 25% quantile; n, number of participants; Normal, between 25% and 75% quantile.