Table 4.
Summary measures at baseline and end of study for participants in the Per Protocol population.
| Baseline |
End of Study |
P |
|
|---|---|---|---|
| Mean (SD) | Mean (SD) | ||
|
Systolic BP (mmHg) | |||
| Placebo (n = 58) | 119.66 (13.82) | 122.86 (14.14) | 0.871missT |
| Lpc-37 (n = 55) |
119.60 (14.21) |
121.87 (14.28) |
|
|
Diastolic BP (mmHg) | |||
| Placebo (n = 58) | 71.68 (9.16) | 74.62 (6.39) | 0.327miss |
| Lpc-37 (n = 55) |
71.89 (7.74) |
73.18 (7.45) |
|
|
STAI-State (score) | |||
| Placebo (n = 58) | 34.33 (7.73) | 35.33 (8.37) | 0.715T |
| Lpc-37 (n = 55) |
33.65 (6.80) |
35.18 (8.38) |
|
|
PSS (score) | |||
| Placebo (n = 57) | 20.72 (7.97) | 21.56 (8.16) | 0.048 |
| Lpc-37 (n = 55) |
21.89 (7.90) |
20.49 (7.51) |
|
|
DASS Depression (score) | |||
| Placebo (n = 58) | 5.21 (6.38) | 5.10 (5.61) | 0.221T |
| Lpc-37 (n = 55) |
4.60 (4.94) |
4.15 (5.52) |
|
|
DASS Anxiety (score) | |||
| Placebo (n = 58) | 3.07 (4.58) | 3.45 (5.08) | 0.224V 0.933B 0.117EOS |
| Lpc-37 (n = 55) |
2.60 (3.35) |
2.44 (3.59) |
|
|
DASS Stress (score) | |||
| Placebo (n = 58) | 9.41 (7.87) | 10.09 (8.17) | 0.248T |
| Lpc-37 (n = 55) |
9.76 (7.92) |
8.91 (7.14) |
|
|
BAI (score) | |||
| Placebo (n = 58) | 5.85 (5.73) | 6.33 (7.26) | 0.099T |
| Lpc-37 (n = 55) |
5.51 (4.46) |
4.75 (4.39) |
|
|
VAS Stress (score) | |||
| Placebo (n = 58) | 19.34 (21.44) | 20.67 (21.63) | 0.436T |
| Lpc-37 (n = 55) |
19.11 (22.97) |
23.32 (23.18) |
|
|
VAS Insecurity (score) | |||
| Placebo (n = 58) | 15.91 (19.60) | 17.30 (20.15) | 0.355V 0.234B 0.344EOS |
| Lpc-37 (n = 55) |
13.58 (21.41) |
16.44 (19.67) |
|
|
VAS Anxiety (score) | |||
| Placebo (n = 58) | 7.58 (14.05) | 7.85 (13.40) | 0.204V 0.362B 0.584EOS |
| Lpc-37 (n = 55) |
7.29 (15.13) |
9.26 (16.48) |
|
|
VAS Exhaustion (score) | |||
| Placebo (n = 58) | 23.19 (21.08) | 18.45 (21.31) | 0.609T |
| Lpc-37 (n = 55) | 29.56 (27.63) | 24.66 (22.78) | |
Abbreviations: BAI, Beck Anxiety Inventory; BP, Blood Pressure; DASS, Depression Anxiety Stress Scale; n, number of participants; PSS, Perceived Stress Scale; SD, Standard Deviation; STAI; State-Trait Anxiety Inventory; VAS, Visual Analog Scale.
V Model assumptions for ANOVA were violated. Change score = baseline vs end of study.
miss Inferential statistics is not based on the same data set as descriptive statistics as records with missing data had to be excluded.
T Outcome was subjected to transformation to meet model assumptions.
B Model assumptions for ANOVA were violated. P value at baseline.
EOS Model assumptions for ANOVA were violated. P value at end of study.