Fig. 3.
Effects of age on (static) functional network connectivity (FNC) between intrinsic connectivity networks (ICNs). (A): FNC matrix showing the pairwise correlations between ICN TCs (FNC) averaged across all participants. Black squares and rectangles highlight ICN pairs for which significant effects for log(Age) were found. (B): The matrix displays the significance and direction of the effects of age for each pairwise correlation (p < 0.05, FDR-corrected). (C, D): Scatterplots depicting how FNC between pairs of ICN TCs changes for increasing age based on two examples from the significant results displayed in (B): (C) is an example of positive age-related correlation (rAGE) between pairwise FNC and age, based on the pair ICN23 (DM) and ICN19 (SMO). (D) Is an example of negative age-related correlation (rAGE) between pairwise FNC and age, based on the pair ICN17 (VIS) and ICN13 (CB). The examples selected for the scatterplots (C) and (D) are highlighted in the FNC matrix (B) with asterisks. Age is presented in the scatterplots (C) and (D) on a log-scale.