Table 2.
Variables collected during and after surgery.
| Nociception Level-guided analgesia | Standard clinical care | Mean or actual difference (95% CI) | P-value | |
|---|---|---|---|---|
| Anaesthesia time (min) | 148 (67) | 133 (45) | 14 (−18 to 46) | 0.377 |
| Surgery time (min) | 130 (63) | 119 (44) | 10 (−21 to 41) | 0.512 |
| End-tidal sevoflurane conc. (%) | 1.6 (0.3) | 1.5 (0.3) | 0.06 (−0.1 to 0.2) | 0.509 |
| Mean bispectral index during surgery | 44 (5) | 44 (6) | 0.05 (−3 to 3) | 0.975 |
| Cumulative fentanyl dose (μg kg−1)∗ | 6.4 (4.2) | 6.0 (2.2) | 0.35 (−1.93 to 2.654) | 0.749 |
| Morphine equivalents during surgery (mg kg−1) | 0.13 (0.04) | 0.14 (0.05) | −0.003 (−0.03 to 0.02) | 0.812 |
| Reversal time (min)† | 9.5 (3.3) | 9.3 (4.8) | 0.2 (−3 to 4) | 0.920 |
| Median pain score in PACU | 3.2 (1.3–4.3) | 4.8 (3–5.3) | 1.6 (0.5–2.7) | 0.006 |
| Morphine equivalents consumed in the PACU (mg kg−1) | 0.06 (0.07) | 0.09 (0.09) | 0.03 (−0.02 to 0.08) | 0.204 |
| Aldrete score 15 min into PACU | 9 (8–9) | 9 (8–9) | 0 | 0.613 |
| Time spent in the PACU (min) | 120 (45) | 115 (44) | 5 (−21 to 31) | 0.711 |
All values are represented as mean (standard deviation), median (inter-quartile range), mean or actual difference (95% confidence interval).
CI, confidence interval
∗
Measured at 120 min into surgery.
†
Time between administration of neuromuscular reversal agent and extubation.