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Number of patients with grade 3–4 toxicities attributable to study therapy
| Cycle1 (n = 11 patients) | Subsequent cycles (n = 9 patients) | |||
|---|---|---|---|---|
| Grade 3 | Grade 4 | Grade 3 | Grade 4 | |
| Neutropenia | 2 | 5 | 3 | 1 |
| Thrombocytopenia | 3 | 2 | 3 | 3 |
| Lymphopenia | 2 | 2 | ||
| Anemia | 5 | 5 | ||
| Fever | 3 | |||
| Febrile neutropenia | 1 | 1 | ||
| Cellulitis | 1 | |||
| Dehydration | 1 | |||
| Dyspnea | 1 | |||
| Fatigue | 1 | |||
| Myalgia | 1 | |||
| ALT elevation | 1 | 1 | ||
| Motor neuropathy | 1 | |||
