Complete response (CR) |
Complete response (CR) |
Disappearance of all target lesions, pathologic lymph nodes must measure short axis < 1 cm |
Disappearance of all non-target lesions, all lymph nodes must measure short axis < 1 cm |
Partial response (PR) |
Non-CR/Non-PD |
At least 30% decrease in sum of diameters of target lesions (relative to baseline sum) |
Persistence of one or more non-target lesions |
Stable disease (SD) |
Progressive disease (PD) |
Not enough tumor shrinkage to qualify as PR, not enough tumor growth to qualify as progression |
Unequivocal progression of existing non-target lesions or any new lesions |
Progressive disease (PD) |
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At least 20% increase in sum of diameters of target lesions (relative to smallest sum), sum must show absolute increase of at least 5 mm, or any new lesions |
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