Representative high-power views of Nampt and CBS IHC. Benign renal cortex Nampt (A) and CBS (B). “*” denotes the proximal renal tubule, the arrow the distal renal tubule and “g” the glomerulus. RO Nampt (C) and CBS (D), renal UC Nampt (E) and CBS (F), Fuhrman grade I Nampt (G) and CBS (H), Fuhrman grade II Nampt (I) and CBS (J), Fuhrman grade III Nampt (K) and CBS (L), Fuhrman grade IV Nampt (M) and CBS (N). G through N are RCC. Nampt, Nicotinamide phosphoribosyltransferase; CBS, cystathionine-β-synthase; UC, urothelial carcinoma; RO, renal oncocytoma; IHC, immunohistochemistry.