Table 3.
ESAS Scores According to Urinary THC Results Among Patients Reporting Cannabinoid Use
| THC-Positive Group Median (LQ; UQ) |
THC-Negative Group Median (LQ; UQ) |
P Valuea | OR (95% CI) | P Valuea,b | |
|---|---|---|---|---|---|
| Total, n (%) | 50 (42.7%) | 67 (57.3%) | |||
| Pain | 7 (5; 7) | 5 (3; 7) | .008 | 1.269 (1.070–1.505) | .006 |
| Fatigue | 6 (4; 8) | 6 (3; 7) | .236 | 1.124 (0.970–1.303) | .121 |
| Drowsiness | 4 (2; 6) | 4 (2; 5) | .421 | 1.075 (0.928–1.246) | .335 |
| Nausea | 1 (0; 3) | 1 (0; 2) | .365 | 1.082 (0.920–1.273) | .339 |
| Appetite | 5 (3; 7) | 2 (0; 5) | <.001 | 1.294 (1.121–1.492) | <.001 |
| Shortness of breath | 2 (0; 4.25) | 1 (0; 4) | .830 | 0.993 (0.862–1.145) | .928 |
| Depression | 3.5 (0.75; 7) | 3 (1; 5) | .353 | 1.117 (0.974–1.281) | .113 |
| Anxiety | 3 (1; 6.25) | 4 (1; 5) | .861 | 1.048 (0.914–1.201) | .503 |
| Overall well-being | 6 (4; 7.25) | 5 (3; 6) | .013 | 1.284 (1.059–1.557) | .011 |
| Spiritual well-being | 5 (2; 6) | 3 (1; 6) | .028 | 1.161 (1.010–1.335) | .036 |
| Constipation | 2.50 (0; 6) | 1 (0; 4) | .411 | 1.119 (0.973–1.286) | .115 |
| Insomnia | 7 (4.75; 8) | 4 (2; 7) | .001 | 1.203 (1.056–1.369) | .005 |
| Total ESAS | 52 (44.75; 64.50) | 40 (29; 54) | .003 | 1.032 (1.010–1.055) | .004 |
Abbreviations: ESAS, Edmonton Symptom Assessment Scale; LQ, lower quartile; OR, odds ratio; THC, tetrahydrocannabinol; UQ, upper quartile.
a
Bold indicates statistically significant P values.
b
Multiple logistic regression for urinary THC results was adjusted for age, sex, and cancer type.