TABLE 1.
Summary information on study participants based on acute gastroenteritis case and control statusa
| Parameter | Value |
|||||
|---|---|---|---|---|---|---|
| HAdV-negative cases (n = 2,718) | HAdV-positive cases (n = 629) | P value comparing cases | HAdV-negative controls (n = 1,258) | HAdV-positive controls (N = 97) | P value comparing controls | |
| Median age (mo) (IQR) | 19.7 (10.1, 45.2) | 16.5 (11.1, 30.6) | 0.002 | 12.1 (4.1, 31.1) | 18.2 (12.1, 38.3) | <0.001 |
| No. of males (%) | 1,437 (52.9) | 369 (58.7) | 0.009 | 665 (52.9) | 57 (58.8) | 0.29 |
| No. of cases in enrollment season (%) | 0.006 | 0.20 | ||||
| January–March | 686 (25.2) | 142 (22.6) | 0.17 | 222 (17.6) | 25 (25.8) | 0.06 |
| April–June | 879 (32.3) | 172 (27.3) | 0.02 | 298 (23.7) | 22 (22.7) | 0.90 |
| July–September | 536 (19.7) | 144 (22.9) | 0.08 | 380 (30.2) | 23 (23.7) | 0.21 |
| October–December | 617 (22.7) | 171 (27.2) | 0.02 | 358 (28.5) | 27 (27.8) | 0.91 |
| No. of HAdV-positive cases (%) | ||||||
| Overall | NA | 629 (100) | NA | 97 (100) | NA | |
| GPP positive | NA | 271 (43.1) | NA | 10 (10.3) | NA | |
| GVP positive | NA | 629 (100) | NA | 97 (100) | NA | |
| GPP positive only | NA | 0 (0) | NA | 0 (0) | NA | |
| GVP positive only | NA | 358 (56.9) | NA | 87 (89.7) | NA | |
| Both GPP and GVP positive | NA | 271 (43.1) | NA | 10 (10.3) | NA | |
| Median Ct value (IQR) | NA | 22.8 (14.5, 32.7) | NA | 32.3 (29.5, 34.2) | NA | |
a
HAdV, human adenovirus; GPP, gastrointestinal pathogen panel; GVP, gastroenteritis virus panel; NA, not applicable; Ct, cycle threshold.