TABLE 3.
Codetection among human adenovirus 40/41 and non-40/41 acute gastroenteritis casesa
| Codetected pathogen | No. of cases (%) |
Difference (%) (95% CI)d | P valued | ||
|---|---|---|---|---|---|
| Overallc (n = 629) | F40/41 (n = 279) | Non-F40/41 (n = 188) | |||
| Any codetection | 250 (39.7) | 47 (16.8) | 95 (50.5) | −33.7 (−42.1, −24.8) | <0.001 |
| Any virus codetection | 225 (35.8) | 36 (12.9) | 89 (47.3) | −34.4 (−42.6, −25.8) | <0.001 |
| Norovirus | 119 (18.9) | 14 (5.0) | 51 (27.1) | −22.1 (−29.5, −15.1) | <0.001 |
| Sapovirus | 62 (9.9) | 15 (5.4) | 27 (14.4) | −10.4 (−16.7, −4.9) | 0.001 |
| Rotavirus | 51 (8.1) | 9 (3.2) | 16 (8.5) | −5.3 (−10.7, −0.7) | 0.02 |
| Astrovirus | 15 (2.4) | 2 (0.7) | 6 (3.2) | −2.5 (−6.5, 0.4) | 0.07 |
| Any bacterium codetection | 31 (4.9) | 10 (3.6) | 9 (4.8) | −1.2 (−5.9, 2.8) | 0.63 |
| Clostridioides difficileb | 10 (1.6) | 5 (1.8) | 2 (1.1) | 0.7 (−3.5, 2.6) | 0.71 |
| Campylobacter spp. | 2 (0.3) | 1 (0.4) | 0 (0) | 0.4 (−2.2, 2.3) | >0.99 |
| Enterotoxigenic Escherichia coli | 2 (0.3) | 1 (0.4) | 1 (0.5) | −0.1 (−3.0, 1.8) | >0.99 |
| Salmonella spp. | 3 (0.5) | 1 (0.4) | 2 (1.1) | −0.7 (−3.9, 1.4) | 0.57 |
| Shiga toxin-producing E. coli | 3 (0.5) | 1 (0.4) | 0 (0) | 0.4 (−2.2, 2.3) | >0.99 |
| Shigella spp. | 1 (0.2) | 1 (0.4) | 0 (0) | 0.4 (−2.2, 2.3) | >0.99 |
| Aeromonas spp. | 6 (1.0) | 0 (0) | 5 (2.7) | −2.7 (−6.4, −0.3) | 0.01 |
| Yersinia spp. | 1 (0.2) | 0 (0) | 0 (0) | NA | NA |
| Any parasite codetection | 4 (0.6) | 2 (0.7) | 0 (0) | 0.7 (−1.9, 2.9) | 0.52 |
| Cryptosporidium | 1 (0.2) | 0 (0) | 0 (0) | NA | NA |
| Entamoeba | 1 (0.2) | 1 (0.4) | 0 (0) | 0.4 (−2.2, 2.3) | >0.99 |
| Giardia | 2 (0.3) | 1 (0.4) | 0 (0) | 0.4 (−2.2, 2.3) | >0.99 |
a
Participants may have had more than 1 codetected pathogen.
b
Children <2.0 years of age in whom C. difficile was detected were considered negative and are not reported in this table.
c
The denominator included all cases that tested positive for adenovirus.
d
Comparison of serogroup F40/41 versus non-F40/41 HAdVs.