Table 1.
Perioperative characteristics divided according to receipt of adjuvant therapy
| Patient characteristics (% or median) | Overall Cohort |
No AT |
Initiated AT |
Initiated, but did not complete AT |
Completed AT |
|---|---|---|---|---|---|
| N = 299 | N = 57 | N = 242 | N = 47 | N = 195 | |
| Age, years | 68 | 74 | 67 | 71 | 67 |
| Male (%) | 57.3 | 65.5 | 54.3 | 53.2 | 54.9 |
| Race (%) | |||||
| White | 90.6 | 96.5 | 90.1 | 93.6 | 89.2 |
| Black | 4.2 | 1.7 | 4.9 | 4.3 | 5.1 |
| Other | 5.2 | 1.7 | 5.0 | 2.1 | 5.6 |
| Body mass index, Kg/m2 | 26.1 | 26.5 | 26.1 | 25.8 | 26.3 |
| Albumin, g/dL | 4.1 | 4 | 4.1 | 4.1 | 4.1 |
| Comorbidity index | 4 | 5 | 4 | 5 | 4 |
| Diabetes (%) | 27.7 | 37.9 | 25.5 | 25.5 | 25.6 |
| Resection (%) | |||||
| Whipple | 72.9 | 74.1 | 72.8 | 61.7 | 75.4 |
| Distal | 21.5 | 19.0 | 21.4 | 27.7 | 20.0 |
| Total/Completion | 5.6 | 6.9 | 5.8 | 10.6 | 5.1 |
| Neoadjuvant (%) | 34.4 | 31.0 | 35.0 | 38.3 | 34.9 |
| Vascular resection (%) | 12.2 | 12.4 | 12.8 | 25.5 | 9.7 |
| Estimated blood loss (cc) | 300 | 350 | 300 | 300 | 275 |
| Operative time (min) | 404 | 457.5 | 398 | 380 | 404 |
| Number of LN resected | 18.5 | 15 | 19 | 21 | 19 |
| Positive 1 Margin (%) | 10 | 8.6 | 9.9 | 12.8 | 9.2 |
| Pathologic Stage (%) | |||||
| 0 (ypT0N0) | 1.0 | 1.7 | 0.82 | 0 | 1.0 |
| 1A | 6.2 | 8.6 | 6.3 | 6.4 | 6.2 |
| 1B | 5.5 | 8.6 | 4.9 | 8.5 | 4.6 |
| 2A | 29.3 | 37.9 | 28.4 | 31.9 | 27.7 |
| 2B | 56.8 | 41.4 | 59.7 | 59.6 | 59.5 |
| 3 | 1.0 | 1.7 | 0.82 | 0 | 1.0 |
| Grade 3–4 complication (%) | 13.6 | 29.3 | 10.7 | 10.6 | 10.8 |
| Length of stay, days | 10 | 12.5 | 10 | 10 | 10 |
| 90-day readmission (%) | 17.7 | 32.8 | 14.0 | 10.6 | 14.9 |
| 90-day mortality (%) | 2.9 | 13.8 | 0.4 | 2.1 | 0.0 |
| AT therapy at MCC (%) | 55.3 | – | 56.0 | 36.2 | 61 |
AT, adjuvant therapy. LN, lymph nodes. Stage 0 patients had complete pathologic response. MCC, Adjuvant therapy performed at Moffitt Cancer Center as opposed to with local care team.