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. 2020 Dec 15;10:607622. doi: 10.3389/fonc.2020.607622

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Copyright © 2020 Xiao, Liu, Li, Xiang, Wang, Li and Xiao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of differentially expressed genes. (A) The volcano plot showed that 524 up-regulated genes (red) and 421 down-regulated genes (green) between osteosarcoma (T) and normal (N) tissues/cells. (B) the volcano plot showed that 808 up-regulated genes (red) and 267 down-regulated genes (green) between high and low immune cell infiltration cluster in TARGET dataset. (C) The volcano plot showed that 245 up-regulated genes (red) and 597 down-regulated genes (green) between high and low immune cell infiltration cluster in GSE42354. (D) Using Draw Venn Diagram to pick up the intersection, 108 differentially expressed genes were obtained.