Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Characteristics of a newly synthesized SKI, KF-1607. (A) The chemical structure of KF-1607 (4-methyl-3-((8-((1-(piperidin-4-yl)-1H-pyrazol-4-yl)amino) imidazo[1,2-a]pyridin-3-yl)ethynyl)-N-(3-(trifluoromethyl)phenyl)benzamide hydrochloride salt). (B) KF-1607 is a potent pan SKI. (C) Kinetic measurement of cytotoxicity using YOYO®-1 iodide reagent, comparing KF-1607 to ponatinib.
