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. 2020 Dec 10;14(12):e0008917. doi: 10.1371/journal.pntd.0008917

Table 4. Clinical characterization of CPP-Jardinópolis patients regarding the percentage of positivity to the clinical criteria used for the diagnosis of leprosy (n = 34) and data about BCG scar in Non-leprosy group distributed according the anti-PGL-I results.

Clinical criteria Yes (n = 34) % anti-PGL-I + (n = 15) % anti-PGL-I—(n = 19) % z p
Dysesthesia hypochromic macular skin lesions 30 88.2 13 86.7 17 89.5 0.25 0.80
    Tactile sensitivity 5 14.7 2 13.3 3 15.8 0.20 0.84
    Tactile + pain sensitivities 6 17.6 5 33.3 1 5.3 2.13 0.03
    Tactile + thermal sensitivities 2 5.9 2 13.3 0 0
    Thermal + tactile + pain sensitivities 17 50.0 5 33.3 12 63.2 1.73 0.08
Dysesthetic areas (without cutaneous signs) 11 32.4 2 13.3 9 47.4 2.11 0.03
    Tactile sensitivity 1 2.9 0 0 1 5.3
    Tactile + pain sensitivities 1 2.9 0 0 1 5.3
    Thermal + tactile + pain sensitivities 10 29.4 2 13.3 8 42.1 1.83 0.07
Localized irregular patches of circumscribed hair loss 25 73.5 12 80.0 13 68.4 0.76 0.45
Altered nerves on palpation (enlargement and/or pain and/or electric shock-like pain) 33 97.1 15 100 18 94.7 0.90 0.37
Endogenous histamine test
    Incomplete 17 50 8 53.1 9 47.4 0.35 0.73
    Not performed 17 50 8 53.1 9 47.4 0.35 0.73
Sweat test (alizarin test)
    Hypohidrosis and/or anhidrosis in islets 4 11.8 1 6.67 3 15.8 0.82 0.41
Leprosy classification
    Borderline 31 91.2 15 100 16 84.2 1.61 0.11
    PNL 3 8.8 1 6.7 2 10.5 0.39 0.70
WHO operational criteria
    Multibacillary 34 100 15 100 19 100 0.0 1.0
WHO impairment grading
    Grade 0 9 28.1 4 26.7 5 26.3 0.01 0.99
    Grade 1 20 62.5 9 60.0 11 57.9 0.12 0.90
    Grade 2 3 0.9 1 6.7 2 10.5 0.39 0.70
    Not evaluated 2 - 1 - 1 -
BCG scar
    0 2 11.8 1 6.7 1 5.3 0.17 0,87
    1 29 85.3 13 86.7 16 78.9 0.59 0.56
    ≥2 1 2.9 0 0 1 3.1
    Not evaluated 2 - 1 - 1 -
BCG scar—NLG
    0 80 20 10.3 60 7.5 1.77 0.08
    1 899 171 87.7 728 90.4 2.38 0.02
    ≥2 21 4 2.0 17 2.1 0.16 0.87
    Not evaluated 216 - 51 - 165 -

PNL: pure neural leprosy; WHO: World Health Organization.