Table 1. Physiological parameters^#1.

Parameter	Symbol(s)	Value
Perfusion of conducting airways	Qbr	7.8 L/h #2
Perfusion of alveolar space	Qalv	312 L/h #3
Bronchial tissue volume	$V_{\text{tis}}^{\text{br}}$	144 mL #4
Alveolar tissue volume	$V_{\text{tis}}^{\text{alv}}$	388 mL #4
Alveolar fluid volume	$V_{\text{flu}}^{\text{alv}}$	36 mL [42]
Alveolar surface area	${\text{SA}}_{\text{flu}}^{\text{alv}}$	130 m2 [43]
Location-resolved parameters	rbr, $a_{\text{flu}}^{\text{br}}$, $a_{\text{tis}}^{\text{br}}$, qbr	see main text

^#1 Physiological parameters were assumed identical for healthy volunteers and asthmatic patients. Only deposition patterns were corrected for asthmatic patients.

^#2 calculated based on 2.5% of cardiac output [44]

^#3 equal to cardiac output, taken from [45, Table 22]

^#4 computed from lung tissue weight of 532 g [45], assuming a tissue density of 1 g/mL and 27% central/73% peripheral lung tissue weight fraction as in [33, Supplement].

Summary of physiological parameters obtained from literature.