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. Author manuscript; available in PMC: 2020 Dec 29.
Published in final edited form as: Hepatoma Res. 2020 Sep 1;6:59. doi: 10.20517/2394-5079.2020.50

Table 1.

AMRI approaches

Sequences Pros Cons
NC-AMRI T1 weighted in-phase and out-of-phase
T2 weighted imaging
Diffusion weighted imaging (DWI)
Cheapest approach
Avoids risk of GBCA
No issues with contrast timing
Relies on unenhanced imaging
Heavily dependent on DWI imaging, which is prone to artifacts in the upper abdomen
HCC may not exhibit restricted diffusion
Dynamic-AMRI Pre-contrast imaging
Arterial phase imaging
Portal venous phase imaging
Delayed phase imaging
Allows definitive diagnosis of HCC
Allows diagnosis of tumor in vein
Cheaper contrast agent options
Inability to detect ancillary features of HCC
Risk of miscategorization of vascular pseudolesions
Dependence on contrast timing, thus repeat imaging requires repeat dose of GBCA or repeat exam
Requires power injector
HBP-AMRI Hepatobiliary phase imaging
T2 weighted imaging
DWI (optional)
High contrast-to-noise
Contrast material can be hand injected in waiting room
Contrast material is retained in the liver for prolonged duration providing a long imaging window and allowing all sequences to be repeated if necessary
Established scoring system based on LI-RADS US
Contrast agent is expensive
Lesions may be obscured by severe cirrhosis
Can detect very early HCCs that cannot be confirmed with currently available call-back tests

AMRI: Abbreviated magnetic resonance imaging; GBCA: gadolinium-based contrast agent; HCC: hepatocellular carcinoma; LI-RADS: Liver Imaging Reporting and Data System; US: ultrasound; HBP: hepatobiliary phase