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. 2020 Dec 29;9(1):e14701. doi: 10.14814/phy2.14701

FIGURE 2.

FIGURE 2

Schematic diagram showing the role of mucins in susceptibility toward COVID‐19. Detection: On the left‐hand side, an epithelial cell of a low‐risk individual shows how the binding of SARS‐CoV2 to the ACE‐2 receptor (shown in blue) is prevented due to steric hindrance by the mucins (shown in green). On the right‐hand side, an epithelial cell of a high‐risk individual shows how the different glycosylation of the mucins (shown in green) aid in binding of the SARS‐CoV2 to ACE‐2 and entry into the cells. Action: Glycome signature of mucins should be used to distinguish between high‐risk and low‐risk groups and will enable the implementation of better quarantine rules in the coming days. Consequence: This will not hamper work and therefore the economy will be stable and also high‐risk groups working from home will help flatten the pandemic curve