Table 2.
The Frequency of Alleles and Genotypes of rs6715375 Polymorphism of miR-375 Gene and Their Comparison in the Case and Control Groups
| miR-375 rs6715345 G>C | Breast cancer group N (%) | Healthy women N (%) | OR (95%CI) | P-value |
|---|---|---|---|---|
| Codominant | ||||
| GG | 164 (80.0) | 164 (82.0) | 1 | - |
| CG | 29 (14.1) | 32 (16.0) | 0.91 (0.52-1.57) | 0.781 |
| CC | 12 (5.9) | 4 (2.0) | 3.00 (0.95-8.63) | 0.071 |
| Dominant | ||||
| GG | 164 (80.0) | 164 (82.0) | 1 | - |
| CG+CC | 41 (20.0) | 36 (18.0) | 1.14 (0.70-1.86) | 0.615 |
| Recessive | ||||
| CG+GG | 193 (94.1) | 196 (98.0) | 1 | - |
| CC | 12 (5.9) | 4 (2.0) | 3.05 (0.97-8.75) | 0.071 |
| Allele | ||||
| G | 357 (87.1) | 360 (90.0) | 1 | - |
| C | 53 (12.9) | 40 (10.0) | 1.34 (0.86-2.07) | 0.225 |