FIGURE 1.
Association of FGF23 and the risk of CKD. CKD was defined as eGFR <60 mL/min/1.73 m2, UAE >30 mg/24 h or both. Data were fitted with a Cox proportional hazards regression model based on restricted cubic splines with three knots and adjusted for (A) age and sex, and additionally for (B) mean arterial blood pressure, the use of antihypertensive drugs, BMI, ethnicity, smoking status, eGFRCKD-EPI, 24-h UAE, total cholesterol, history of diabetes, plasma phosphate, calcium, PTH, 25(OH)D, hsCRP and 24-h urine urea excretion.