Table 2.
MBD parameters and therapies: changes over the first year of dialysis
| Timing of measurement |
|||
|---|---|---|---|
| Patient characteristics | Immediately prior to HD initiation | First month after HD initiation | 9–12 months after HD initiation |
| CKD-MBD parameters | |||
| PTH (pg/mL) | 275 (155–472) | 253 (143–435) | 253 (148–409) |
| Serum phosphorus (mg/dL) | 5.3 ± 1.8 | 4.9 ± 1.5 | 5.1 ± 1.5 |
| Serum calcium (mg/dL) | N/A | 8.8 ± 0.8 | 9.0 ± 0.7 |
| 25(OH)D (ng/mL) | N/A | 23.7 ± 16.4 | 27.2 ± 13.0 |
| Alkaline phosphatase (U/L) | N/A | 83 (65–115) | 85 (66–116) |
| CKD-MBD therapies | |||
| Dialysate calcium (mEq/L) | N/A | 2.6 ± 0.3 | 2.6 ± 0.3 |
| Phosphate binder, any (%) | N/A | 53 | 78 |
| Ca-based (%) | N/A | 35 | 45 |
| Non-Ca based (%) | N/A | 18 | 33 |
| Calcimimetic (%) | N/A | 3 | 8 |
| Active vitamin D, any (%) | N/A | 48 | 62 |
| IV (%) | N/A | 18 | 35 |
| Oral (%) | N/A | 33 | 30 |
| Oral nutritional vitamin D (%) | N/A | 20 | 23 |
Values are shown as mean ± standard deviation, median (interquartile range) or %; N/A: not available, as information on treatments (and most laboratory values) prior to HD initiation was not collected in DOPPS.