Table 4.

Serum biochemistry and phosphate-related hormones in rats with adenine-induced CKD

Parameters	Normal	CKD
Phosphate (mg/dL)	7.1 ± 0.1	9.0 ± 0.4*
Calcium (mg/dL)	10.6 ± 0.1	10.7 ± 0.1
BUN (mg/dL)	21.2 ± 0.5	109.8 ± 5.5*
Creatinine (mg/dL)	0.26 ± 0.01	1.51 ± 0.09*
FGF23 (pg/mL)	1291 ± 170	14765 ± 2826*
Intact PTH (pg/mL)	143 ± 8	888 ± 117*
Calcitriol (pg/mL)	128 ± 16	14 ± 6*

Values are expressed as mean ± SE (n = 10).

^*P < 0.05, significant difference versus normal control rats (Student’s t-test).

Normal, normal rats; CKD, adenine-induced CKD rats.