Table 5. Final treatment outcomes for RR-TB/MDR-TB patients enrolled in 2012 and 2015.
| Final Treatment outcome | 2012 Baseline | 2013 | 2014 | 2015 | P-value |
|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | n (%) | (X2) | |
| Total | 41 | 203 | 205 | 241 | |
| Cured¥ | 20(48.8) | 122(60.1) | 142(69.3) | 161(66.8) | 0.03 |
| CompletedØ | 12(29.3) | 28(13.8) | 10(4.9) | 8(3.3) | <0.05 |
| TSR* | 32(78.0) | 150(73.9) | 152(74.1) | 169(70.1) | 0.63 |
| Unfavorable | 9(22.0) | 53(26.1) | 53(25.9) | 72(29.9) | |
| • Lost to Follow up | 4(9.7) | 15(7.4) | 22(10.7) | 34(14.1) | 0.16 |
| • Died | 2(4.9) | 36(17.7) | 30(14.6) | 34(14.1) | 0.20 |
| • Failed Treatment | 0(0.0) | 2(1.0) | 1(0.5) | 4(1.7) | 0.57 |
| • Not evaluated | 3(7.3) | 0(0.0) | 0(0.0) | 0(0.0) | <0.05 |
| Tested for HIV | 41(100) | 203(100) | 205(100) | 241(100) | |
| HIV-positive | 13(31.7) | 91(44.8) | 109(53.2) | 138(57.3) | <0.05 |
| Started on CPT | 13(100) | 91(100) | 109(100) | 138(100) | |
| Started on ART | 13(100) | 91(100) | 109(100) | 138(100) |
N/n = Number of patients. *From 2015 cohort 9 patients were found not RR/MDR patients and thus eliminated from final treatment outcomes
¥Cured is a pulmonary TB patient with bacteriologically confirmed TB at the beginning of treatment who was smear- or culture-negative in the last month of treatment and on at least one previous occasion.
Ø Treatment completed is a TB patient who completed treatment without evidence of failure BUT with no record to show that sputum smear or culture results in the last month of treatment and on at least one previous occasion were negative, either because tests were not done or because results are unavailable.
*TSR (Treatment Success Rate) is the sum of cure rate and completion rate.
HIV—human immunodeficiency virus, CPT—Co-trimoxazole preventive therapy, ART–antiretroviral therapy, X2 for the trend.