Table 3.
Effect of single dose AIRE on hyperglycemia in STZ-induced diabetic mice.
| Blood glucose level (mg/dl) | |||||
|---|---|---|---|---|---|
| Group | 0 hr | 2 hr | 4 hr | 6 hr | 8 hr |
| DW10 ml/kg | 391.6 ± 2.249 | 386.2 ± 5.877 | 395 ± 1.581 | 393.8 ± 1.497 | 395.4 ± 1.600 |
| AIRE100 mg/kg | 416 ± 27.817 | 382 ± 19.514 | 365 ± 10.124 | 369 ± 9.894 | 253 ± 9.160Axβy |
| AIRE200 mg/kg | 377.4 ± 21.970 | 358.4 ± 18.10 | 343.6 ± 16.336 | 339.2 ± 12.816 | 317.6 ± 10.671AxBxβy |
| AIRE400 mg/kg | 393 ± 11.176 | 368.6 ± 14.038 | 362 ± 17.283 | 349.2 ± 19.523 | 313.4 ± 8.897AxBxβy |
| GLC mg/kg | 376.4 ± 8.698 | 282.6 ± 2.960Axβy | 197.2 ± 4.224Axβz | 178.2 ± 2.653AyBxCxDxβz | 168 ± 3.975az bxcxdxβz |
N = 6 for each treatment; each value is presented in mean ± SEM. ACompared to the negative control; βcompared to the baseline blood glucose level; Bcompared to 100 mg/kg AIRE; Ccompared to 200 mg/kg AIRE; Dcompared to 400 mg/kg AIRE. xp < 0.05;yp < 0.01; zp < 0.001. DW, distilled water; GLC, glibenclamide; AIRE, Ajuga integrifolia root extract.