Table 6.
The activity of single doses of three fractions of AIRE on hyperglycemia in STZ-induced diabetic mice.
| Blood glucose level (mg/dl) | |||||
|---|---|---|---|---|---|
| Group | 0 hr | 2 hr | 4 hr | 6 hr | 8 hr |
| DW10 ml/kg | 391.6 ± 5.03 | 393.2 ± 3.023 | 391.6 ± 4.261 | 388.6 ± 3.487 | 391.8 ± 2.223 |
| AQA100 mg/kg | 415.8 ± 62.311 | 396 ± 34.095 | 401.6 ± 10.870 | 394 ± 5.621 | 388.4 ± 27.817 |
| AQA200 mg/kg | 375.4 ± 52.600 | 336.2 ± 22.030 | 316.8 ± 21.224 | 323.4 ± 19.065 | 312.7 ± 23.376AxCxHxβx |
| AQA400 mg/kg | 393 ± 24.900 | 354.2 ± 18.940 | 359.4 ± 10.539 | 334.6 ± 7.004 | 309.8 ± 5.643AxCxHxβx |
| HX100 mg/kg | 376.4 ± 8.698 | 384.8 ± 5.526 | 372.4 ± 14.590 | 370 ± 9.560 | 377.8 ± 11.508 |
| HX200 mg/kg | 387 ± 12.892 | 373.2 ± 16.451 | 399.4 ± 11.830 | 413 ± 16.257 | 378.6 ± 10.722 |
| HX400 mg/kg | 395.6 ± 15.045 | 421.2 ± 16.488 | 418.6 ± 11.927 | 394.2 ± 5.544 | 430.4 ± 24.330 |
| CHL100 mg/kg | 385.8 ± 8.470 | 388.2 ± 3.917 | 399 ± 9.365 | 390.2 ± 15.160 | 397.2 ± 9.754 |
| CHL200 mg/kg | 394.2 ± 8.381 | 405.2 ± 17.080 | 407.8 ± 24.800 | 418.6 ± 13.851 | 401.2 ± 11.770 |
| CHL400 mg/kg | 386.8 ± 7.179 | 380.2 ± 5.324 | 306 ± 12.779 | 406.4 ± 8.334 | 387.8 ± 4.375 |
| GBC5 mg/kg | 376.4 ± 19.450 | 292.6 ± 8.004Axβx | 240.9 ± 8.213Axβx | 199.2 ± 8.399Ayβy | 134.6 ± 3.842Azβz |
N = 6 for each treatment group; each value is presented in mean ± SEM. ACompared to negative control; βcompared to baseline; Bcompared to 100 mg/kg; Ccompared to chloroform; Hcompared to hexane. xp < 0.05;yp < 0.01; zp < 0.001. AQA, aqueous; HX, hexane; CH, chloroform; GLC, glibenclamide.