Table 7.
The activity of repeated daily doses of aqueous fraction of AIRE against hyperglycemia in STZ-induced diabetic mice.
| Blood glucose level (mg/dl) | |||||
|---|---|---|---|---|---|
| Group | Baseline BGL | BGL at 7th day | BGL at 14th day | 7th day R (%) | 14th day R (%) |
| DW10 ml/kg | 391.6 ± 5.030 | 429.2 ± 33.041 | 489.2 ± 43.101 | −9.58 | −24.85 |
| AQA100 mg/kg | 415.8 ± 62.311 | 379.19 ± 25.203Axβxnx | 372.8 ± 26.329Axβxnx | 7.93 | 9.43 |
| AQA200 mg/kg | 375.4 ± 52.681 | 311.20 ± 35.181AyBxβxnx | 296.2 ± 36.093AyBxβxnx | 16.76 | 20.52 |
| AQA400 mg/kg | 393 ± 24.990 | 306.21 ± 20.584AyBxβxnx | 286 ± 21.91AyBxβxnx | 22.13 | 23.89 |
| GLC5 mg/kg | 376.4 ± 19.45 | 146.6 ± 16.607AyBzCxDy βynx | 135.2 ± 6.907 AzBzCyDyβzn1 | 61.3.0 | 64.10 |
| Normal control | 82.6 ± 4.231 | 81.9 ± 2.890 | 82.8 ± 1.931 | 0.840 | −0.20 |
N = 6 for each group; each value is presented in mean ± SEM. ACompared to diabetic control; βcompared to baseline; Bcompared to 100 mg/kg; Ccompared to 200 mg/kg; Dcompared to 400 mg/kg; ncompared to normal control. xp < 0.05;yp < 0.01; zp < 0.001. GLC, glibenclamide; AQA, aqueous; DW, distilled water; R, reduction.