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. 2020 Dec 21;2020:6687143. doi: 10.1155/2020/6687143

Figure 3.

Figure 3

HSD reduced the number of effective NK cells in the spleen and inhibited their maturation in both the spleen and bone marrow. Representative flow cytometry profiles (a). The percentage (b) and absolute number (c) of NK cell subsets DN (CD27−CD11b−), CD27SP (CD27+CD11b−), DP (CD27+CD11b+), and CD11bSP (CD27−CD11b+) in the spleen and BM of control and HSD-fed mice. Representative flow cytometry profiles (d). The percentage (e) and absolute number of NKp (NK1.1−CD11b−), imNK (NK1.1+CD11b−), and mNK (NK1.1+CD11b+) cells gated on CD3− CD122+ splenocytes and bone marrow cells of control and HSD-fed mice. All the data represent at least three independent experiments. Data are shown as the means ± SEM. Unpaired Student's t-tests (two-tailed) were performed using the Prism software. A P value of <0.05 was considered significant. ∗P < 0.05, ∗∗P < 0.01.