Scheme 10.
A) Retrosynthesis and B) total synthesis of (−)-lingzhiol. (R)-CBS = (R)-Corey-Bakshi-Shibata oxazaborolidine, HMDS = bis(trimethylsilyl)amide, NBS = N-bromosuccinimide, p-TSA = para-toluenesulfonic acid.
A) Retrosynthesis and B) total synthesis of (−)-lingzhiol. (R)-CBS = (R)-Corey-Bakshi-Shibata oxazaborolidine, HMDS = bis(trimethylsilyl)amide, NBS = N-bromosuccinimide, p-TSA = para-toluenesulfonic acid.