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. Author manuscript; available in PMC: 2020 Dec 29.
Published in final edited form as: Angew Chem Int Ed Engl. 2020 Aug 24;59(43):18898–18919. doi: 10.1002/anie.201915657

Scheme 15.

Scheme 15.

Synthesis of GB22 according to Shenvi and co-workers. dF(CF3)ppy = 3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl]phenyl, dtbbpy = 4,4’-di-tert-butyl-2,2’-dipyridyl.