Table 2.
Matched data for sex, education, age and MMSE in patients with AD versus DD
| Neuropsychological assessment | AD (n = 63) | DD (n = 63) | P-value | R 2 |
|---|---|---|---|---|
| Median/IQR | Median/IQR | |||
| Age (years) | 76.0/70.0–80.0 | 75.0/69.0–80.0 | 0.756 | <0.01 |
| GDS | 5.0/2.0–8.5 | 6.0/4.0–10.0 | 0.045 | 0.03 |
| MMSE | 26.0 ± 25.0–28.0 | 27.0 ± 25.0–29.0 | 0.138 | 0.02 |
| CVLT1 | 3.0/2.0–4.0 | 3.0/2.0–4.0 | 0.075 | 0.03 |
| CVLT5 | 5.0/4.0–7.0 | 7.0/5.0–9.0 | 0.000 | 0.13 |
| CVLT total recall | 21.0/18.0–28.0 | 27.5/22.8–34.3 | 0.000 | 0.11 |
| CVLT delayed recall | 1.0/0.0–3.8 | 4.0/2.8–7.0 | 0.000 | 0.21 |
| CVLT delayed cued recall | 4.0/2.0–6.0 | 6.5/5.0–9.0 | 0.000 | 0.16 |
| CVLT recognition | 14.0/11.3–15.0 | 14.0/12.8–15.0 | 0.520 | <0.01 |
| CVLT false positive | 6.5/3.3–12.8 | 2.5/1.0–5.3 | 0.000 | 0.10 |
| Digit span forward | 7.0/6.0–8.0 | 6.0/5.0–8.0 | 0.371 | 0.01 |
| Digit span backward | 4.0/3.0–5.0 | 4.0/3.0–5.3 | 0.649 | <0.01 |
| Block span forward | 6.0/5.0–7.0 | 6.0/5.0–7.0 | 0.168 | 0.02 |
| Block span backward | 5.0/3.0–6.0 | 5.0/4.0–6.0 | 0.833 | <0.01 |
| Clock drawing | 3.0/2.0–4.0 | 3.0/2.0–3.0 | 0.044 | 0.03 |
| TMT-A | 71.0/54.0–119.0 | 58.5/40.5–101.0 | 0.021 | 0.04 |
| TMT-B | 199.0/154.0–249.0 | 170.5/119.5–248.0 | 0.077 | 0.03 |
| Semantic fluency | 14.0/11.0–17.0 | 15.0/12.0–20.0 | 0.078 | 0.03 |
| Phonematic fluency P | 5.0/3.0–7.0 | 6.0/3.0–8.0 | 0.138 | 0.02 |
| Phonematic fluency S | 7.5/5.0–10.8 | 7.0/5.0–10.0 | 0.768 | <0.01 |
Abbreviations: AD, Alzheimer’s disease; CVLT, California Verbal Learning Test; DD, depressive disorder; GDS, Geriatric Depression Scale; MMSE, Mini-Mental Status Examination; TMT-A, Trail-Making Test A; TMT-B, Trail-Making Test B.