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. 2020 Dec 16;11:565730. doi: 10.3389/fimmu.2020.565730

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Copyright © 2020 Pretti, Galvani, Vieira, Bonomo, Bonamino and Boroni

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Unsupervised two-dimensional cluster analysis of 37 countries by HLA-A and HLA-B Allele frequencies. Each row represents a population, the first column represents the deaths per million inhabitants quartiles: Q1 = green (lower than 5); Q2 = yellow (5 to 20); Q3 = orange (21 to 85); Q4 = red (greater than 85). The other columns represent HLA alleles, which frequencies values are represented by the blue scale color bar. The complete method and 1-Pearson correlation coefficient as distance were used to cluster rows and columns.