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Elevated sympathetic fiber (SFs) density in aged tissues. (A,B) SFs were identified by immunohistochemistry (IHC) with anti-tyrosine hydroxylase (TH) antibodies in brain, liver, spleen tissue and lung tissue samples from naturally aged mice (n = 3), and human colon adenoma tissue samples (n = 10), **P < 0.01, bars, mean ± SD, scale bar, 30 μm. The cerebral hemisphere parenchyma in brain was employed for IHC experiments.
