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. 2020 Dec 29;10:22418. doi: 10.1038/s41598-020-80120-8

Figure 5.

Figure 5

Upstream regulator–downstream plasma DEP network. The upstream regulators that were known or reported to regulate the input DEPs at the upper level were searched, and their status was calculated using the Ingenuity Pathway Analysis bioinformatics tool. Eight regulators were predicted to be upregulated and one to be downregulated. The upstream regulators, their regulation targets, that is, plasma DEPs in our dataset, and the functional connections between them were plotted.