Figure 4.

Pancreatic deletion of IL-1α does not modify energy expenditure (EE), respiratory exchange ratio (RER), physical activity, or food intake. (A) EE at daily intervals showing light cycle (white) or dark cycle (grey), and (B) mean EE over a 6-d period. (C) Respiratory exchange rate (RER) at daily intervals, and (D) mean RER over a 6-d period. (E) Activity, as measured by the number of X and Y beam breaks segregated by light (white) and dark cycle (grey shading), and (F) total activity over a 6-d period. (G) Total food (g) and (H) total liquid consumed (g) in male IL-1α^fl/fl and IL-1α^Pdx1−/− mice given by light (black bars) and dark cycle (white bars). n = 8 per group.