Figure 2.

Reported associations of serum and CSF cytokine levels with ICANS. All published studies that reported association of cytokine measurements with ICANS are summarized. The first column shows the ICANS grades that were compared to determine whether there was an association of cytokine levels with either presence or absence of ICANS in half of the studies, or between none/mild and severe ICANS in the other half. In studies that reported CSF cytokine measurements, baseline samples were compared to those obtained during acute ICANS.