Fig. 5.

(a–d). Quantitative expression of a) GRP 78, b) GRP 94, c) CHOP and d) Caspase-12 genes by Real time PCR in different treatment groups viz. vehicle control, restrain, imipramine, MEEP (100 mg/kg) and MEEP (200 mg/kg) in mice hippocampus with restrain stress. Gene expression was normalized to that of β actin. Values are expressed as fold change represented as Mean ± SEM (n = 3). Statistical significance was determined by one-way ANOVA followed by Tukey's post hoc test ^###p < 0.001 when compared to vehicle control; ***p < 0.001 when compared to restrain group.