Table 4.
Summarized table of Kyoto Encyclopedia of Genes and Genomes metabolic pathways at day 4, 6, and 10 comparing 1% ChT–fed birds and control birds.
| Metabolic pathways |
Day 4 |
Day 6 |
Day 10 |
|||
|---|---|---|---|---|---|---|
| Identified pathways | Number of peptides | P-value | Number of peptides | P-value | Number of peptides | P-value |
| PI3K-Akt signaling pathway | 34 | 1.15 × 10−22 | 44 | 4.28 × 10−29 | 24 | 1.11 × 10−13 |
| MAPK signaling pathway | 30 | 1.75 × 10−20 | 49 | 2.32 × 10−37 | 22 | 2.44 × 10−13 |
| Metabolic pathway | 28 | 1.39 × 10−05 | 32 | 4.67 × 10−05 | - | - |
| Insulin signaling pathway | 27 | 5.29 × 10−25 | 27 | 1.30 × 10−22 | 20 | 7.77 × 10−17 |
| AMPK signaling pathway | 21 | 1.19 × 10−18 | 20 | 7.95 × 10−16 | 16 | 3.16 × 10−13 |
| HIF-1 signaling pathway | 18 | 1.82 × 10−16 | 18 | 5.60 × 10−15 | 12 | 6.91 × 10−10 |
| mTOR signaling pathway | 18 | 6.72 × 10−14 | 18 | 2.23 × 10−12 | 18 | 5.53 × 10−14 |
| cAMP signaling pathway | 17 | 2.85 × 10−11 | 13 | 1.79 × 10−06 | - | - |
| Glucagon signaling pathway | 14 | 8.32 × 10−12 | 15 | 1.22 × 10−11 | 11 | 9.36 × 10−09 |
| VEGF signaling pathway | 12 | 7.40 × 10−12 | 17 | 7.06 × 10−17 | - | - |
| Calcium signaling pathway | 11 | 2.42 × 10−06 | 10 | 0.00012 | - | - |
| Glycolysis/Gluconeogenesis | 10 | 5.39 × 10−09 | 10 | 4.75 × 10−08 | - | - |
| GnRH signaling pathway | 10 | 4.43 × 10−08 | 14 | 3.03 × 10−11 | - | - |
| Adipocytokine signaling pathway | - | - | 18 | 3.60 × 10−17 | - | - |
The hyphens indicate less than 10 peptides and not significant for our analysis.
Abbreviation: ChT, chestnut tannin.