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. Author manuscript; available in PMC: 2020 Dec 30.
Published in final edited form as: Biochem J. 2020 Oct 16;477(19):3899–3910. doi: 10.1042/BCJ20200440

Figure 1. Dopamine and carbidopa as AhR ligands in Caco2 and U87 cells.

Figure 1.

Cells were treated with DMSO (control) 10 nM TCDD, 10–100 µM dopamine, and carbidopa alone in or in combination with 10 µM CH233191, and induction of CYP1A1 (A), CYP1B1 (B), and UGT1A1 (C) was determined by real-time PCR as outlined in the Methods. Results are expressed as means ± SD for at least three replicates for each treatment group and significant (P < 0.05) induction (*) or inhibition by CH223191 (**) is indicated.