Table 4.
The effects of osteocalcin on liver function and lipid biochemical indexes in high-fat diet fed aged laying hens.
| Parameters | ND + V | HFD + V | HFD + OCN | SEM | P |
|---|---|---|---|---|---|
| AST (U/L) | 157.40 | 147.06 | 142.41 | 9.82 | 0.32 |
| ALP (U/L) | 285.1b | 1,139.7a | 978.3a | 42.79 | 0.008 |
| TC (mmol/L) | 2.75 | 2.07 | 2.97 | 0.64 | 0.35 |
| TG (mmol/L) | 12.06 | 11.98 | 12.59 | 2.28 | 0.96 |
| LDL-C (μmol/L) | 312.08 | 325.45 | 321.27 | 9.77 | 0.40 |
| HDL-C (μmol/L) | 198.15 | 202.86 | 200.73 | 5.80 | 0.73 |
a, b Mean ± SEM with different capital letter in the same row differ significantly (n = 10, P < 0.05).
Abbreviations: ALP, alkaline phosphatase; AST, aspartate transaminase; HDL-C, high density lipoprotein cholesterol; HFD + OCN, high-fat diet + osteocalcin; HFD + V, high-fat diet + vehicle; ND + V, normal diet + vehicle; LDL-C, low density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride.