Table 5.
Changes in quality of life
|
Control (n = 21)
|
P
value
|
Intervention (n = 22)
|
P
value
|
|||
|
Baseline
|
Final
|
|
Baseline
|
Final
|
|
|
| CLDQ questionnaire | ||||||
| Abdominal symptoms | 5.4 ± 1.3 | 5.2 ± 0.8 | 0.592 | 5.0 ± 1.5 | 5.1 ± 1.2 | 0.982 |
| Fatigue | 4.7 ± 1.1 | 5.2 ± 0.8 | 0.063 | 4.2 ± 1.2 | 5.1 ± 1.2 | 0.000 |
| Systemic symptoms | 5.6 ± 1.0 | 5.6 ± 0.9 | 0.892 | 4.3 ± 1.2 | 5.0 ± 0.9 | 0.002 |
| Activity | 5.3 ± 1.2 | 5.3 ± 1.3 | 0.892 | 4.8 ± 1.2 | 5.5 ± 1.2 | 0.028 |
| Emotional function | 4.9 ± 0.9 | 5.3 ± 1.1 | 0.056 | 4.3 ± 1.3 | 5.3 ± 1.0 | 0.000 |
| Worry | 5.1 ± 1.1 | 5.3 ± 1.1 | 0.521 | 4.3 ± 1.8 | 5.2 ± 1.8 | 0.002 |
| CLDQ overall score | 5.2 ± 0.8 | 5.4 ± 0.9 | 0.204 | 4.6 ± 1.0 | 5.3 ± 0.8 | 0.001 |
| SF-36 questionnaire | ||||||
| Physical function | 80 (70-90) | 95 (80-95) | 0.005 | 72.5 (65-95) | 87.5 (70-95) | 0.007 |
| Physical role | 75 (25-100) | 100 (50-100) | 0.166 | 62.5 (25 -100) | 75 (25-100) | 0.468 |
| Body pain | 84 (66-90) | 84 (72-90) | 0.341 | 78 (61-84) | 78 (60-84) | 0.725 |
| General health | 40 (37-47) | 47 (35-52) | 0.044 | 40 (25-55) | 42 (32-52) | 0.375 |
| Vitality | 65 (50-70) | 70 (60-75) | 0.453 | 62.5 (50-75) | 70 (50-80) | 0.037 |
| Social function | 100 (75-100) | 88 (75-100) | 0.875 | 75 (63-100) | 88 (75-100) | 0.080 |
| Emotional role | 67 (33-83) | 67 (33-67) | 0.972 | 67 (33-72) | 67 (33-67) | 0.752 |
| Mental health | 72 (68-84) | 84 (64-88) | 0.868 | 76 (64-84) | 82 (68-92) | 0.073 |
Data reported as mean ± standard deviation, or median (p25-p75), according to the distribution of the data. CLDQ: Chronic liver disease questionnaire; SF-36: 36-item short form health survey.