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. 2020 Dec 27;12(12):1258–1266. doi: 10.4254/wjh.v12.i12.1258

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Pre- vs post-treatment computed tomography scans of the liver. A: Liver computed tomography (CT) scan before treatment with proprotein convertase subtilisin/kexin type-9 (PCSK9) inhibitor, showing the liver to be homogeneously hypodense (< 40 HU) and the portal and hepatic veins to have unclear delineation from the surrounding parenchyma; B: Liver CT scan after treatment with PCSK9 inhibitor, showing the liver to have increased density and the portal and hepatic veins to be clear (i.e., linear hypodense structures, in contrast to the more hyperdense liver parenchyma).