Table 1.
Effect of administration of T. bellirica fruit extracts and ellagic acid on the body weight and relative liver weight of diclofenac treated rats for 21 days. Group-I: control rats; Group-II: DCF treated rats; Group-III: DCF + SLM treated rats; Group-IV: DCF + EA treated rats; Group-V: DCF + AQ treated rats; Group-VI: DCF + Eth treated rats. Each value is expressed in mean ± SD (n = 5). Abbreviations: DCF- diclofenac, SLM- silymarin, EA- ellagic acid, AQ- aqueous extract, Eth- ethyl acetate extract. (*) represents a significant difference from control (p < 0.0001). (#) represents a significant difference from group II (p < 0.005).
| Groups | Bodyweight Change (%) |
Absolute liver Weight (g) |
Relative liver Weight (%) |
|---|---|---|---|
| Group-I | 17.82 ± 3.03 | 4.24 ± 0.06 | 2.35 ± 0.09 |
| Group-II | −18.54 ± 1.78* | 7.44 ± 0.28* | 4.31 ± 0.07* |
| Group-III | −6.99 ± 1.57# | 4.79 ± 0.10# | 3.06 ± 0.07# |
| Group-IV | −8.86 ± 0.78# | 5.39 ± 1.21# | 3.26 ± 0.35# |
| Group-V | −11.59 ± 1.06# | 5.89 ± 0.21# | 3.56 ± 0.08# |
| Group-VI | −9.05 ± 4.70# | 6.40 ± 0.22# | 2.99 ± 0.01# |