TABLE 1.
Drug | Citations | Mechanism of action | |
1 | Aciclovir | World Health Organization (2020) | Nucleoside analog |
2 | Amantadine | World Health Organization (2020) | Interferes with transmembrane M2 protein |
3 | Amprenavir | World Health Organization (2020) | Protease inhibitor (HIV) |
4 | Baloxavir marboxil | Xie et al. (2020) | Endonuclease inhibitor—inhibits the initiation of mRNA synthesis |
5 | Darunavir | Zhang et al. (2020) | Second generation protease inhibitor |
6 | Entecavir | World Health Organization (2020) | Guanine analogue (HCV) |
7 | Faldaprevir | World Health Organization (2020) | HCV protease inhibitor |
8 | Faviparivir | Beigel et al. (2019) | Prodrug of a purine nucleotide, favipiravir ribofuranosyl-5′-triphosphate—RNA polymerase inhibitor |
9 | Galidesivir | Mayer et al. (2015) | Protease inhibitor—Adenine analog |
10 | GS-441524 | Xie et al. (2020) | Adenisin nucleoside analog |
11 | Indinavir | World Health Organization (2020) | HIV protease specific inhibitor |
12 | Lopinavir | Beigel et al. (2019) | Aspartic acid protease (HIV) inhibitor |
13 | Nelfinavir | Vellingiri et al. (2020) | Protease inhibitor |
14 | Oseltamivir | Vellingiri et al. (2020) | Active neuraminidase inhibitor |
15 | Pleconaril | Xie et al. (2020) | Viral capsid inhibitor |
16 | Remdesivir | Cheng (2019) | Prodrug—active nucleoside analog C-adenosine triphosphate—(Ebola) |
17 | Ribavirin | Kang et al. (2020) | Nucleoside analogue (guanine)—inhibits viral RNA-dependent RNA polymerase |
18 | Sofosbuvir | Glushkov et al. (1999) | Nucleoside analog—hepatitis C virus NS5B polymerase inhibitor |
19 | Tenofovir | Glushkov et al. (1999) | Acyclic nucleoside analog adenosine monophosphate |
20 | Tipranavir | Xie et al. (2020) | HIV protease enzyme inhibitor |
21 | Umifenovir | Zhou et al. (2020) | Hemagglutinin inhibitor (influenza) |
22 | Zanamivir | World Health Organization (2020) | Neuraminidase inhibitor |