Table 1.

Examples of Evidence-Based Strategies for Clinical Organizations to Address COVID-19 Vaccine Hesitancy at the Interpersonal and Individual Level

Interpersonal strategies
Strategy	Example
Make recommendations	“Your clinician recommends that you get the COVID-19 vaccine.”
Make strong recommendations.	“COVID-19 vaccination is safe and effective, and I strongly recommend that you to get your COVID-19 vaccine today.”
Use presumptive-style language.	“After this visit, the nurse will give you your COVID-19 vaccine.”

Individual strategies
Strategy	Example
Frame messages in terms of gain	“Getting the COVID-19 vaccine will protect you and your family.”
Offer novel information about the disease	“We are learning that COVID-19 infections can result in longer-lasting and debilitating health problems such as fatigue, headaches, joint pain, and sleep difficulty.”
Appeal to altruism and prosocial behavior	“Getting the COVID-19 vaccine not only protects you, it will also protect the people you care about including your family and friends.”
Address patient barriers and use effective approaches to countering misperceptions	Affirm values: “I know you care deeply about [protecting the health of your loved ones; doing what is right for your community; taking good care of your health; protecting your family], and getting the COVID-19 vaccine can help you do so.”
	Explain motivation for misinformation: “Your concern(s) about [vaccine safety; adverse effects; vaccine need; vaccine timing] is a common misperception that has been sensationalized in popular media.”
	Repeat factual information: “Substantial evidence exists regarding [the safety of the COVID-19 vaccine that has been documented in tens of thousands patients; the temporary and mild nature of adverse effects; the need for the COVID-19 vaccine to protect individuals and to end the pandemic; the need for individuals to get vaccinated as soon as the vaccine becomes available to them].”

COVID-19, coronavirus disease 2019.