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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Plast Reconstr Surg. 2021 Jan 1;147(1):54e–65e. doi: 10.1097/PRS.0000000000007451

Figure 4. Skeletal Stem Cell Hierarchy.

Figure 4.

(A) The skeletal stem cell hierarchy in mice beginning with a self-renewing mouse Skeletal Stem Cell (mSSC) differentiating to lineage-restricted bone, cartilage, and stromal cells through a Bone, Cartilage, Stromal Progenitor (BCSP) cell8. (B) The skeletal stem cell hierarchy in humans beginning with a self-renewing human Skeletal Stem Cell (hSSC) differentiating to lineage-restricted bone, cartilage, and stromal cells through a Bone, Cartilage, Stromal Progenitor (BCSP) cell9.