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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Am J Surg Pathol. 2020 Dec;44(12):1677–1684. doi: 10.1097/PAS.0000000000001575

Figure 4. Histologic features of the molecular negative subset of RHE and CHE.

Figure 4.

(A-B) YAP1-negative RHE. (A; 14/M, shoulder) Low power view showing dilated blood vessels within dermis lined by hobnail endothelial cells. (B; 55/M, thigh) Elongated, tubular vascular channels lined by cuboidal hyperchromatic endothelial cells, embedded in a stroma with abundant lymphocytic infiltrate. (C,D) CHE lacking YAP1 or MAML2 gene rearrangements. (C; 24/F, scalp) Predominant retiform areas with a focal epithelioid component arranged in single files. (D; 36/F, scalp) A variegated appearance showing solid, single cells as well as hemangioma-like areas.