Table 7. Pathway analysis of genes differentially expressed between DACH1 mutated patients and wild-type.
Ingenuity Canonical Pathways | -log(p-value) |
---|---|
1. Breast Cancer Regulation by STMN1 | 3.45 |
2. Catecholamine Biosynthesis | 3.19 |
3. Transcriptional Regulatory Network in Embryonic Stem Cells | 3.19 |
4. Serotonin and Melatonin Biosynthesis | 2.53 |
5. Methionine Salvage II (Mammalian) | 2.06 |
6. FXR/RXR Activation | 2.01 |
7. LPS/IL-1 Mediated Inhibition of RXR Function | 1.9 |
8. Stearate Biosynthesis I (Animals) | 1.86 |
9. Complement System | 1.83 |
10. Thyroid Hormone Metabolism II (via Conjugation and/or Degradation) | 1.77 |