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. 2020 Dec 30;15(12):e0244558. doi: 10.1371/journal.pone.0244558

Table 7. Pathway analysis of genes differentially expressed between DACH1 mutated patients and wild-type.

Ingenuity Canonical Pathways -log(p-value)
1. Breast Cancer Regulation by STMN1 3.45
2. Catecholamine Biosynthesis 3.19
3. Transcriptional Regulatory Network in Embryonic Stem Cells 3.19
4. Serotonin and Melatonin Biosynthesis 2.53
5. Methionine Salvage II (Mammalian) 2.06
6. FXR/RXR Activation 2.01
7. LPS/IL-1 Mediated Inhibition of RXR Function 1.9
8. Stearate Biosynthesis I (Animals) 1.86
9. Complement System 1.83
10. Thyroid Hormone Metabolism II (via Conjugation and/or Degradation) 1.77