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. Author manuscript; available in PMC: 2020 Dec 30.
Published in final edited form as: Biochem J. 2020 Oct 30;477(20):3923–3934. doi: 10.1042/BCJ20200351

Figure 3. HSP90 inhibitors ameliorate pyroptosis in THP-1 cells.

Figure 3.

17-DMAG (A), Radicicol (B) and 17-AAG (C) were added to THP-1 cells at indicated concentration 1 h before pyroptosis induction with LPS and Nigericin as in Figure 2. The cell culture supernatant LDH and cell viability were analyzed 60 min after Nigericin treatment. N = 3–4. *p < 0.05 versus 0.