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. 2020 Dec 30;14(3):389–416. doi: 10.1016/j.jiph.2020.12.025

Table 9.

Different phases of vaccination.

Phases evaluation Actions Reference
Phase 1 In a small number of closely monitored subjects, immunogenicity and safety studies performed. [287]
Phase 2 Enroll hundreds of subjects and do dose-ranging studies.
Phase 3 Provide critical documentation about important and effectiveness additional safety data required for licensing by enrolling thousands of people